目的 为了深入研究短梗五加茎的活性物质基础。方法 利用硅胶柱色谱、Sephadex LH-20等多种色谱法对短梗五加茎的化学成分进行研究。结果 鉴定了15个化合物的结构,分别为商陆素(Ⅰ)、金合欢素(Ⅱ)、槲皮素(Ⅲ)、 金丝桃苷(Ⅳ)、5a,8a-桥二氧麦角甾-6,22-双烯-3-醇(Ⅴ)、芝麻脂素(Ⅵ)、β-谷甾醇(Ⅶ)、胡萝卜苷 (Ⅷ)、咖啡酸(Ⅸ)、没食子酸(Ⅹ)、原儿茶酸(Ⅺ)、山柰酚(Ⅻ)、山柰苷(ⅩⅢ)、异秦皮啶-7-O-α-D-吡喃葡萄糖苷(ⅩⅣ)、豆甾醇-3-O-β-D-吡喃葡萄糖苷(XV)。结论 化合物Ⅰ、Ⅱ、Ⅴ、Ⅻ、ⅩⅢ、ⅩⅣ和ⅩⅤ均首次从该植物中分离得到。
Abstract
OBJECTIVE To study the active substances of Acanthopanax sessiliflorus (Rupr. Et Maxim.)Seem for better using the traditional Chinese medicine.METHODS The constituents from the stem of the A. sessiliflorus were studied by various chromatographies such as column chromatography. RUSULTS Fifteen compounds were isolated by the column chromatography and elucidated as ombuin(Ⅰ), acacetin(Ⅱ), quercetin(Ⅲ), hyperoside(Ⅳ), 5a,8a-epidioxy-(22E, 24R)-ergosta-6, 22-dien-3β-ol(Ⅴ),(-)-sesamin(Ⅵ), β-sitosterol(Ⅶ), daucosterol(Ⅷ), caffeic acid(Ⅸ), gallic acid(Ⅹ), protocatechuic acid(Ⅺ), kaempferol(Ⅻ), kaempferitrin(ⅩⅢ), isofraxidin-7-O-α-D-glucoside(ⅩⅣ) and stigmasterol-3-O-β-D-glucopyranoside (ⅩⅤ) by spectral data and hydrolysis methods. CONCLUSION CompoundⅠ, Ⅱ, Ⅴ, Ⅻ, ⅩⅢ, ⅩⅢ, ⅩⅣ and ⅩⅤ are isolated from the species for the first time.
关键词
短梗五加 /
黄酮 /
酚酸 /
苯丙素 /
商陆素 /
金合欢素
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Key words
Acanthopanax sessiliflorus /
flavone /
phenolic acid /
phenylpropanoid /
ombuin /
acacetin
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中图分类号：
R284.1
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参考文献
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脚注
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基金
吉林农业大学博士启动基金(201008)
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